Billionaire investor Mark Cuban’s Cost Plus Drugs is now part of a major expansion of the federal government’s discounted medication website TrumpRx, adding more than 600 generic medications to a platform that the White House says has been visited more than 10 million times since its February launch.

President Donald Trump announced the expansion at a White House event Monday, calling TrumpRx “the hottest thing in medicine.” The additions increase the site’s offerings by nearly seven times, the administration said.

The expansion is made possible by partnerships with other online pharmacies, including Amazon Pharmacy, GoodRx and Cuban’s Cost Plus Drugs.

How TrumpRx Works

TrumpRx is not a platform for buying medications. Instead, it is set up as a facilitator, pointing Americans to drugmakers’ direct-to-consumer websites where they can make purchases. It also provides coupons to use at pharmacies. The site initially launched in February with over 40 medications.

The beefed-up website is the administration’s response to criticism that the original platform offered limited savings. It also marks an effort to respond to a top voter concern: affordability. Health costs are a worry for many Americans, an issue compounded by recent cuts to Medicaid and the expiration of enhanced Affordable Care Act subsidies this year.

Mark Cuban’s Role

Cuban, a political independent who publicly campaigned for Democrat Kamala Harris in the 2024 presidential election, has enthusiastically advocated for TrumpRx and the work that some in the U.S. Department of Health and Human Services are doing to make prescription drugs cheaper.

Before Monday, Cuban had said the one thing Trump could do to make the government’s version better would be to add the drugs available on his own site.

“Everyone wants me to rip on TrumpRx,” Cuban wrote in a recent social media post. “Reality is, it’s saving patients money on IVF and a few other drugs. A lot of money.”

Trump and Cuban were congenial at Monday’s event. “We have the same thing, one thing in common: We want to make people better and keep them wealthy,” Trump said.

What It Means for Texans

Texas has one of the highest rates of uninsured residents in the country, and affordability of prescription drugs is a persistent concern. The TrumpRx expansion, with its focus on generic medications, could provide meaningful savings for Texans who pay out of pocket. For more on Dallas business and health care, visit Business of Dallas.

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